Substrate specificity of protein kinase C inhibitors.
نویسندگان
چکیده
In the August issue of TiPS, Epand and Lester analysed the effect of the physicochemical properties of the membrane on protein kinase C activity. In addition to those substrates discussed that require the presence of Ca2+ and phospholipids, other substrates can be phosphorylated in the absence of these activators. It is possible that this differential substrate requirement could be exploited pharmacologically.
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ورودعنوان ژورنال:
- Trends in pharmacological sciences
دوره 11 12 شماره
صفحات -
تاریخ انتشار 1990